Why we chose it: Retinols work, but they can also be irritating to some skin types. This serum uses purified peptides that act like retinol, but are way gentler (and can be used morning and night). In addition to its hydrating, firming, and toning properties, this serum is tested and developed by dermatologists, and it’s clinically proven to be gentle on sensitive skin.

Cetaphil’s Healthy Renew face serum is ideal for users who have adverse reactions to using retinol. The purified peptides in this serum do the same job as retinol: reduce the signs of aging like fine lines and wrinkles.

Where retinol increases cell turnover, making your skin more sensitive, peptides stimulate collagen production, which makes your skin stronger and more firm.

The serum is formulated to target 5 different signs of skin sensitivity: dryness, roughness, a weakened barrier, tightness, and irritation. Though some users do report it works for there skin, there are others who have had adverse reactions to this serum.

Make sure to patch test any new skincare product to observe for any irritation or reactions.